Egli Marcel HSLU T&A

Prof. Dr. Marcel Egli Marcel Egli

Leiter Institut für Medizintechnik

Egli Marcel HSLU T&A

Hochschule Luzern – Technik & Architektur

Raum 311
Obermattweg 9
6052 Hergiswil NW


Institut für Medizintechnik IMT

Leiter Institut für Medizintechnik

Dozent

+41 41 349 36 18

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Biografie

Marcel Egli is head of the Institute of Medical Engineering at the Lucerne University of Applied Sciences and Arts that combines the Centre of Competence in Bioscience and Medical Engineering, the "Space Biology Group" and the User Support and Operational Centre “BIOTESC” that serves the European Space Agency ESA. The Institute offers study programmes as well as complementary post-graduate courses.

Marcel Egli became first a precision mechanic before he entered the academic career. He started off by earning a master’s degree in zoology from the University of Berne. Thereafter, he enrolled into a multi-disciplinary graduate school (medicine and biology) at the same University. After completion, he spent several years as a postdoctoral fellow at the University of Melbourne (Howard Florey Institute, Australia) and at the Florida State University (Department of Biology, USA). There, he became Associate Faculty and focused on studying secretory rhythms of hormones in mammals. Later on, the appointment to lead the Space Biology Group at ETH Zurich brought him back to Switzerland. He received the Venia Legendi from ETH Zürich in space biology after submitting the habilitation thesis. A few years later, he moved his research group from Zurich to Lucerne, where the Institute of Medical Engineering was founded.

Marcel Egli has published numerous scientific articles in the fields of neurobiology, neuro-endocrinology, and more recently in space biology. His current research interests include mainly the cellular mechanisms of mechanosensation, induced by mechanical unloading (e.g. weightlessness). For conducting such research, not only regular laboratory instruments are employed but also research platforms like airplanes performing parabolic flight manoeuvres, sounding rockets as well as the laboratories of the International Space Station ISS.

Projekte

Forschungsprojekte

  • Space Bioreactor
  • Real Estate Investment und Asset Management (REAM)
  • HSLU Medtech Joint Venture
  • CIMProW - Circular Innovation: Medical Protective Wear
  • Standard for Space Bioreactors
  • Reparatur und Regeneration der Bandscheibe
  • CaSiPaC - Calcium Signaling during Parabolic Flight in Chondrocytes
  • ITC - Protective Wear. Gestaltung und Designgeschichte von Schutzkleidung
  • Plant Physiology under Microgravity
  • COW – Cartilage ExpOsed to Weightlessness
  • SpaceFab - an algal biomodule for a nanosatellite
  • Hefezellen im All - Yeast Bioreactor
  • SaNuInvest - Sanierungsstrategien unter Berücksichtigung des Nutzungszyklus aus Sicht institutioneller Investoren
  • Swiss Parabolic Flight 2016
  • Gelenkknorpel
  • Sustainable Manufacturing Concepts in Space - A European Space Agency Project
  • Sustainable Manufacturing Concepts in Space - A European Space Agency Project
  • Rexus CEMIOS
  • Mathematische Modelle in der Medizin
  • Zytotoxizität von Abgasen aus Holzfeuerungen
  • MGI Phase II CC MS
  • Micro-Gravity Incubator (MGI)

Publikationen und Präsentationen

Publikationen und Präsentationen - Buch/Katalog

  • Egli, Marcel (Hrsg.). (2017). Sounding rocket and balloon activities and related research in Switzerland 2015 – 2017. Proceedings of the 23st ESA Symposium on European rocket and balloon programmes and related research. Switzerland: ESA.
  • Egli, Marcel (Hrsg.). (2011). Sounding rocket and balloon activities and related research in Switzerland 2009 – 2011: Proceedings of the 21sr ESA Symposium on European rocket and balloon programmes and related research. Switzerland: ESA.
  • Egli, Marcel & Cogoli-Greuter, M (Hrsg.). (2009). Sounding rocket and balloon activities and related research in Switzerland 2007 – 2009: Proceedings of the 19th ESA Symposium on European rocket and balloon programmes and related research. Switzerland: ESA.

Publikationen und Präsentationen - Artikel, Rezension; peer reviewed

  • Abdelfattah, Fatima; Corydon, Thomas J.; Egli, Marcel; Graf, Jenny; Grimm, Daniela; Infanger, Manfred; Kraus, Armin; Krüger, Marcus; Sahana, Jayashree; Schulz, Herbert; Wehland, Markus; Wise, Petra M. & Wüest, Simon (2024). Omics Studies of Tumor Cells under Microgravity Conditions. International Journal of Molecular Sciences, doi: https://doi.org/10.3390/ijms25020926
  • Hammer, Andreas; Cerretti, Geraldine; Ricciardi, Dario A.; Schiffmann, David; Maranda, Simon; Kummer, Raphael; Zumbühl, Christoph; Rattenbacher-Kiser, Karin; von Arx, Silvan; Ammann, Sebastian; Strobl, Frederic; Berkane, Rayene; Stolz, Alexandra; Stelzer, Ernst H.K.; Egli, Marcel; Schleiff, Enrico; Wuest, Simon L. & Böhmer, Maik (2022). Retrograde Analysis of Calcium Signaling by CaMPARI2 Shows Cytosolic Calcium in Chondrocytes Is Unaffected by Parabolic Flights. Biomedicines, 1.
  • Hammer, Andreas; Cerretti, Geraldine; Ricciardi, Dario A.; Schiffmann, David; Maranda, Simon; Kummer, Raphael; Zumbühl, Christoph; Rattenbacher-Kiser, Karin; von Arx, Silvan; Ammann, Sebastian; Strobel, Frederic; Berkane, Rayene; Stolz, Alexandra; Stelzer, Ernst H. K.; Egli, Marcel; Schleiff, Enrico; Wuest, Simon & Böhmer, Maik (2022). Retrograde Analysis of Calcium Signaling by CaMPARI2 Shows Cytosolic Calcium in Chondrocytes Is Unaffected by Parabolic Flights. Biomedicines, 2022(1), 1-21. doi: 10.3390/biomedicines10010138
  • Bradley, Timothy; Cerretti, Geraldine; Egli, Marcel; Follonier, Cindy; Ille, Fabian; Rattenbacher-Kiser, Karin; Wadsworth, Jennifer Louise & Wüest, Simon (2022). Cytosolic calcium and membrane potential in articular chondrocytes during parabolic flight. Acta Astronautica, 2022(193), 287-302.
  • Cortéz-Sanchéz, José-Luis; Corydon, T J; Egli, Marcel; Grimm, Daniela; Hemmersbach, R; Infanger, M.; Kraus, Armin; Krüger, Markus; Sahana, J; Schulz, Herbert; Wehland, M. & Wise, Petra (2022). The Fight against Cancer by Microgravity: The Multicellular Spheroid as a Metastasis Model. International Journal of Molecular Science, 23(6), 33.
  • Han, Yilin; Zeger, Lukas; Tripathi, Rekha; Ille, Fabian; Atic, Edwin; Egli, Marcel; Florin, Gunnar; Fredriksson, Robert; Kozlova, Elena; Lockowandt, Christian & Redwan, Itedale (2021). Molecular Genetic Analysis of Neural Stem Cells After Space Flight And Simulated Microgravity on Earth. Europe PMC, 12-20.
  • Calio, Martina; Gantenbein, Benjamin; Egli, Marcel; Poveda, Lucy & Ille, Fabian (2021). The Cellular Composition of Bovine Coccygeal Intervertebral Discs: A Comprehensive Single-Cell RNAseq Analysis. International Journal of Molecular Science, 22(4917),
  • Egli, Marcel; Ehrig, Rainald; Fischer, Sophie; Ille, Fabian; Krüger, THC; Leeners, B.; Mancini, T; Röblitz, Susanna; Schäfer, Stefan & Tronci, E (2021). Mathematical Modeling and Simulation Provides Evidence for New Strategies of Ovarian Stimulation.. Frontiers in Endocrinology, 33.
  • Egli, Marcel; Garaedts, K; Hengartner, M P; Ille, Fabian; Krüger, THC; Leeners, B.; Röblitzy, S.; Schippert, C & Tronci, E (2021). Cognitive function in association with high estradiol levels resulting from fertility treatment.. Hormones and Behaviour, (130), 47.
  • Bauer, J.; Corydon, T J; Egli, Marcel; Grimm, Daniela; Kopp, S.; Krüger, M; Lebert, M.; Prasad, B.; Richter, P & Wehland, M (2020). The effects of microgravity on differentiation and cell growth in stem cells and cancer stem cells Tissue Engineering and Regenerative Medicine. Stem cells translational medicine, 9(8), 98.
  • Castiglioni, Sara; Cazzaniga, Alessandra; Egli, Marcel; Giger, Christina; Haack, Carsten; Ille, Fabian; Koller, Adrian; Maier, Jeanette; Wüest, Simon & Zocchi, Monika (2020). Scalable Microgravity Simulator Used for Long-Term Musculoskeletal Cells and Tissue Engineering. Molecular Science, Volume 21, Issue 23(Special Issue "Molecular Mechanobiology in Space and on Earth), 44.
  • Wüest, Simon; Arnold, Jaro; Gander, Sarah; Zumbühl, Christoph; Jost, Christian; Giger, Christina; Cerretti, Geraldine; Caliò, Martina; Rattenbacher-Kiser, Karin; Follonier, Cindy; Schälli, Othmar; Székely, Gerhard Stefan; Egli, Marcel & Ille, Fabian (2020). Microtubules and Vimentin Fiber Stability during Parabolic Flights. Microgravity Science and Technology, 2020, 1. doi: https://doi.org/10.1007/s12217-020-09818-8
  • Baatout, S; Krüger, M; Evert, M; Bauer, J.; Pietsch, J.; Corydon, T J; Infanger, M.; Grimm, D.; Egli, Marcel; Kobbero, SD; Melnik, D; Moreels, M; Nebuloni, S; Sahana, J; Wehland, M; Carvalho, D.; Gass, S. & Koop, S. (2019). Growth of Endothelial Cells in Space and in Simulated Microgravity – a Comparison on the Secretory Level.. Cellular Physiology and Biochemistry, (52), 1039-1060.
  • Zotter, Peter; Richard, S.; Egli, Marcel; Rothen-Rutisauser, B & Nussbaumer, Thomas (2019). A simple method to determine cytotoxicity of water-soluble organic compounds and solid particles from biomass combustion in lung cells in vitro.. Environ Sci Technol, (53), 3959-3968.
  • Krüger, M; Wehland, M; Bauer, J.; Egli, Marcel; Kopp, S.; Corydon, T J; Infanger, M.; Moreels, M; Baatout, S & Grimm, Daniela (2019). Growing Blood Vessels in Space: Preparation Studies of the SPHEROIDS Project using Related Ground-Based Studies.. Acta Astronautica, (159), 267-272.
  • Lye Yee Yap, Jasmine; Beyer, Christian; Bharanty, N; Casarosa, M; Foo, Zi LIng; Egli, Marcel; Franco-Obregon, A.; Fröhlich, J; Hui Hua Fong, Charlene; Kala Palanchamy, M; Lee, C. N.; Tai, Yee Kit; Taneja, R; Toh, Shi Jie & Yin, N (2019). Ambient and supplemental magnetic fields promote myogenesis via a TRPC1-mitochondrial axis: Evidence of a magnetic mitohormetic mechanism. FASEB Journal, 33(10), 33-38.
  • Granata, Timothy; Habermacher, Patrick; Härri, Vinzenz & Egli, Marcel (2019). The influence of bio optical properties of Emiliania huxleyi and Tetraselmis sp. on biomass and lipid production when exposed to different light spectra and intensities of an adjustable LED array and standard light sources.. Nature Applied Science, (524), 1.
  • Leeners, B.; Krüger, THC; Geraedts, K; Tronci, E; Mancini, T; Egli, Marcel; Röblitzy, S.; Saleh, L; Spanaus, K; Schippert, C; Zhang, Y & Ille, Fabian (2019). Associations Between Natural Physiological and Supraphysiological Estradiol Levels and Stress Perception. Front. Psychol., (1296), 10.
  • Liu, G.; Bollier, D; Gübeli, Ch; Arnold, P.; Borghi, L; Peter, N. & Egli, Marcel (2018). Simulated microgravity and the antagonistic influence of strigolactone on plant nutrient uptake in low nutrient conditions.. Nature Microgravity, (4), 20-20.
  • Franco-Obregón, Alfredo; Cambria, E.; Greutert, H.; Wernas, Timon; Hitzl, W; Egli, Marcel; Sekiguchi, M; Boos, N.; Ferguson, S J; Hausmann, O.; Kobayashi, H. & Wuertz-Kozak, K. (2018). TRPC6 in simulated microgravity of intervertebral disc cells.. Eur Spine J., (27), 2621-2630.
  • Grimm, D.; Egli, Marcel; Krüger, M; Riwaldt, S; Corydon, T J; Kopp, S.; Wehland, M; Wise, P.; Infanger, M.; Mann, V. & Sundaresan, A (2018). Tissue Engineering under Microgravity Conditions – Use of Stem Cells and Specialized Cells.. Stem Cells and Development, (27), 787-804.
  • Wüest, Simon; Gantenbein, Benjamin; Ille, Fabian & Egli, Marcel (2018). Electrophysiological experiments in microgravity: lessons learned and future challenges. npj Microgravity, 2018, 1-7. doi: 10.1038/s41526-018-0042-3
  • Wüest, Simon; Caliò, Martina; Wernas, Timon; Tanner, Samuel; Giger, Christina; Wyss, Fabienne; Ille, Fabian; Gantenbein, Benjamin & Egli, Marcel (2018). Influence of Mechanical Unloading on Articular Chondrocyte Dedifferentiation. Ing.J.Mol.Sci., 19(5), 1-18.
  • Wüest, Simon; Plüss, Tobias; Hardegger, Christoph; Felder, Mario; Kunz, Aaron; Fleischli, Benno; Komotar, Carlos; Rüdlinger, Lukas; Albisser, Andreas; Gisler, Thomas; Frauchiger, Daniela & Egli, Marcel (2017). Electrophysiological Recordings on a Sounding Rocket: Report of a First Attempt Using Xenopus laevis Oocytes. Gravitational and Space Research, 5(2), 43-56.
  • Egli, Marcel; Casartelli, Ernesto; Stern, Philip & Wüest, S L (2017). Fluid Dynamics Appearing during Simulated Microgravity Using Random Positioning Machines.. PLoS ONE, 12, 170.
  • Egli, Marcel; Geraedts, K; Hengartner, M P; Ille, Fabian; Kruger, THC; Leeners, B.; Mancini, T; Röblitzy, S.; Saleh, L; Schippert, C; Spanaus, K; Tronci, E & Zhang, Y (2017). Lack of Associations between Female Hormone Levels and Visuospatial Working Memory, Divided Attention and Cognitive Bias across Two Consecutive Menstrual Cycles.. Front. Behav. Neurosci, 11:120.
  • Egli, Marcel; Baake, C; Bauer, J.; Corydon, T J; Echegoyen, D; Gass, Thomas; Grimm, D.; Infanger, M.; Nebuloni, S; Pietsch, J. & Riwaldt, S (2017). Three-dimensional growth of human endothelial cells in an automated cell culture experiment container during the SpaceX CRS-8 ISS space mission - The SPHEROIDS Project.. Biomaterials, 124, 126-156.
  • Egli, Marcel; Ehrig, Frank; Garaedts, K; Hengartner, M P; Ille, Fabian; Kruger, THC; Leenres, B; Mancini, T; Röblitzy, S.; Saleh, L; Schippert, C; Spanaus, K; Tronci, E & Zhang, Y (2017). Negative affect is unrelated to fluctuations in hormone levels across the menstrual cycle: Evidence from a multisite observational study across two successive cycles.. Journal of Psychosomatic Research., 99, 21-27.
  • Wüest, Simon; Rösch, Christian; Ille, Fabian & Egli, Marcel (2017). Calcium dependent current recordings in Xenopus laevis oocytes in microgravity. Acta Astronautica, 141, 228-236. doi: https://doi.org/10.1016/j.actaastro.2017.10.003
  • Wüest, Simon; Stern, Philip; Casartelli, Ernesto & Egli, Marcel (2017). Fluid Dynamics Appearing during Simulated Microgravity Using Random Positioning Machines. PLOS ONE, 1-19. doi: https://doi.org/10.1371/journal.pone.0170826
  • Casartelli, Ernesto; Egli, Marcel; Stern, Philip & Wuest, Simon L. (2017). Fluid Dynamics Appearing during Simulated Microgravity Using Random Positioning Machines. PLoS ONE, 2017,
  • Brungs, Sonja; Christianen, Peter C. M.; Egli, Marcel; Hemmersbach, Ruth; Ngo Anh, Thu Jennifer; van Loon, Jack J. W. A. & Wüest, Simon (14.01.2016). Facilities for Simulation of Microgravity in the ESA Ground-Based Facility Programme. Microgravity Science and Technology, 28(3), 191-203.
  • Aleshcheva, G; Bauer, Johann; Hemmersbach, R; Egli, Marcel; Wehland, M & Grimm, D. (29.12.2015). Tissue Engineering of Cartilage on Ground-Based Facilities. Microgravity Sci Technol, 2015(11), 265-276.
  • Egli, Marcel; Aleshcheva, G; Hemmersbach, R; Wehland, M & Grimm, D. (2016). Tissue Engineering of Cartilage on Ground-Based Facilities. Microgravity Science and Technology, 237-245.
  • Wüest, Simon; Richard, Stéphane; Kopp, Sascha; Grimm, Daniela & Egli, Marcel (2015). Simulated Microgravity: Critical Review on the Use of Random Positioning Machines for Mammalian Cell Culture. BioMed Research International, 2015(Article ID 971474), 2-8.
  • Aleshcheva, G; Wehland, M; Sahana, J; Bauer, J.; Hemmersbach, R; Frett, T; Infanger, M.; Grosse, J; Grimm, D. & Egli, Marcel (2015). Moderate alterations of the cytoskeleton in human chondrocytes after short-term microgravity produced by parabolic flight maneuvers could be prevented by up-regulation of BMP-2 and SOX-9. FASEB Journal, 23.
  • Benavides Damm, Tatiana; Walther, I.; Wüest, Simon; Sekler, Jörg & Egli, Marcel (2014). Cell cultivation under different gravitational loads using a novel random positioning incubator. Biotechnol Bioeng, 111, 1180-1190.
  • Benavides Damm, Tatiana & Egli, Marcel (2014). Calcium's Role in Mechanotransduction during Muscle Development. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2014(2), 249-272. doi: 10.1159/000356667
  • Wüest, SL; Richard, S.; Walther, I.; Furrer, R.; Anderegg, R.; Sekler, Jörg & Egli, Marcel (2014). Novel Microgravity Simulator Applicable for Three-Dimensional Cell Culturing. Microgravity Sci Technol, (26), 77-88.
  • Benavides Damm, Tatiana; Isabelle, Walther; Wüest, Simon; Sekler, Jörg & Egli, Marcel (2014). Cell Cultivation Under Different Gravitational Loads Using a Novel Random Positioning Incubator. Biotechnology and Bioengineering, 111(6), 1180-1190. doi: 10.1002/bit.25179
  • Damm, Tatiana Benavides; Richard, Stéphane; Tanner, Samuel; Wyss, Fabienne; Egli, Marcel & Franco-Obregón, Alfredo (2013). Calcium-dependent deceleration of the cell cycle in muscle cells by simulated microgravity [Besprechung des Buchs FASEB Journal]. FASEB Journal, 2013, 2045-2054.
  • Benavides Damm, Tatiana; Richard, S.; Tanner, S.; Wyss, F.; Egli, Marcel & Franco-Obregón, Alfredo (2013). Calcium-Dependent Deceleration of the Cell Cycle by Simulated Microgravity. FASEB Journal, (27), 2045-2054.
  • Benavides Damm, Tatiana; Franco-Obregón, Alfredo & Egli, Marcel (2013). Gravitational Force Modulates G2/M Phase Exit in Mechanically Unloaded Myoblasts. Cell Cycle, (12), 3001-3012.
  • Walther, I.; Cogoli, M. & Egli, Marcel (2013). Microgravity Cell Culture Systems and Bioreactors: Current Status and Future Developments. Current Biotechnology, 2013(12), 244-249.
  • Aleshcheva, G; Infanger, M.; Hemmersbach, R; Bauer, J.; Hauslage, J; Sahana, J; Egli, Marcel & Grimm, D. (2013). Changes in Morphology, Gene Expression and Protein Content in Chondrocytes cultured on a Random Positioning Machine. PLoS One, (8), e79057.
  • Crocetti, S; Beyer, Ch; Shade, G; Egli, Marcel & Franco-Obregón, Alfredo (2013). Low intensity and frequency pulsed electromagnetic fields provide a method to selectively kill breast cancer cells. PLoS One, (8), e72944.
  • Leeners, B.; Kruger, THC; Brody, S; Schmidlin, S; Naegeli, E & Egli, Marcel (2013). Prolactin increases after orgasm correlate with quality of sexual experience in women. J Sex Med, (10), 1313-9.
  • Grosse, J; Wehland, M; Pietsch, J.; Ma, X.; Ulbrich, C.; Schulze, H.; Saar, K; Hübner, N; Hauslage, J; Hemmersbach, R; Braun, M; van Loon, J; Vagt, N; Infanger, M.; Egli, Marcel; Richter, P; Baltz, Th; Einspanier, R; Sharbati, S; Eilles, Ch & Grimm, D. (2012). Short-term weightlessness produced by parabolic flight maneuvres altered gene expression patterns in human endothelial cells. FASEB Journal, 639-655.
  • Richard, S.; Ille, F.; Forster, I.; Franco-Obregón, Alfredo & Egli, Marcel (2012). A semi-automated electrophysiology system for recording from Xenopus oocytes under microgravity conditions. Microgravity Sci Technol, 237-244.
  • Faith Toy, M.; Depeursinge, C; Parent, J; Richard, S. & Egli, Marcel (2012). Accelerated autofocusing of off-axis holograms using critical sampling. Biomed Opt Express, 313-326.
  • Kruger, THC; Leeners, B.; Naegeli, E; Schmidlin, S; Schedlowski, M; Hartmann, U & Egli, Marcel (2012). Prolactin secretory rhythm in females: Immediate and long-term alterations after sexual contact. Hum Reprod, 1139-1143.
  • Pietsch, J.; Sickmann, A.; Weber, G.; Bauer, J.; Wildgruber, R.; Egli, Marcel; Infanger, M. & Grimm, D. (2012). Metabolic enzyme diversity in different human thyroid cell lines and their sensitivity to gravitational forces. Proteomics, 2012(12), 2539-25.
  • Faith Toy, M.; Kühn, J.; Franco-Obregón, Alfredo; Depeursinge, C & Egli, Marcel (2012). Enhanced robustness digital holographic microscopy for demanding environments. Biomed Opt Express, 313-326.
  • Richard, S.; Henggeler, D.; Ille, Fabian; Vadrucci, S; Moeckli, M.; Forster, I.; Ian, C.; Franco-Obregón, Alfredo & Egli, Marcel (2012). A Semi-automated Electrophysiology System for Recording from Xenopus Oocytes Under Microgravity Conditions. Microgravity Science and Technology, (24), 237-244.
  • Schaffhauser, DF; Andrini, O; Ghezzi, Ch.; Franco-Obregón, Alfredo; Dittrich, PS & Egli, Marcel (2011). Microfluidic platform for electrophysiological studies on Xenopus laevis oocytes under varying gravity levels. Lab on a Chip, (11), 3471-3478.
  • Sirzen-Zelenskaya, A.; Gonzalez-Iglesias, AE; Boutet de Monvel, J.; Bertram, R.; Freeman, ME; Gerber, U. & Egli, Marcel (2011). Prolactin-induced inhibition of electrical activity of rat paraventricular oxytocinergic neurons. J Neuroendocrinol, (23), 883-893.
  • Pietsch, J.; Sickmann, A.; Weber, G.; Bauer, J.; Wildgruber, R.; Infanger, M.; Grimm, D. & Egli, Marcel (2011). A proteomic approach to analyzing spheroid formation of two human thyroid cell lines cultured on a random positioning machine. Proteomics, (11), 2095-2104.
  • Ulbrich, C.; Pietsch, J.; Grosse, J; Wehland, M; Schulze, H.; Saar, K; Hübner, N; Hauslage, J; Hemmersbach, R; Braun, M; van Loon, J; Vagt, N; Richter, P; Einspanier, R; Sharbati, S; Baltz, Th; Infanger, Kurt; Grimm, D. & Egli, Marcel (2011). Differential gene regulation under altered gravity conditions in follicular thyroid cancer cells: Relationship between extracellular matrix and the cytoskeleton. Cell Physiol Biochem, (28), 185-198.
  • Pietsch, J.; Sickmann, A.; Bauer, J.; Weber, G.; Nissum, M; Westphal, K; Egli, Marcel; Grosse, J; Schönberger, J; Eilles, Ch; Infanger, M. & Grimm, D. (2011). Proteome analysis of thyroid cancer cells after long-term exposure to a random positioning machine. Microgravity Sci Technol, 381-390.
  • Pietsch, J.; Bauer, J.; Infanger, M.; Grimm, M & Egli, Marcel (2011). The effects of weightlessness on the human organism and mammalian cells. Curr Mol Med, (11), 350-364.
  • Monici, M; Cialdai, F; Romano, G; Pezzatini, S; Morbidelli, L & Egli, Marcel (2011). An in Vitro Study on Tissue Repair: Impact of Unloading on Cells Involved in the Remodelling Phase. Microgravity Sci. Technol, (23), 391-401.
  • Leeners, B.; Kruger, THC & Egli, Marcel (2010). Prolactin secretion patterns: basic mechanisms and clinical implications for reproduction. Reproduction, (140), 643-654.
  • Ulbrich, C.; Westphal, K; Pietsch, J.; Winkler, HDF; Leder, A; Bauer, J.; Kossmehl, P; Grosse, J; Schönberger, J; Grimm, D.; Infanger, M. & Egli, Marcel (2010). Characterization of human chondrocytes exposed to simulated microgravity. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, (25), 551-560.
  • Mauclaire, L & Egli, Marcel (2010). Effect of simulated microgravity on growth and production of exopolymeric substances of Micrococcus luteus space and earth isolates. FEMS Immunol Med Microbiol, (59), 350-356.
  • Pietsch, J.; Kussian, R; Sickmann, A.; Bauer, J.; Weber, G.; Nissum, M; Westphal, K; Grosse, J; Schönberger, J; Wildgruber, R.; Infanger, M.; Grimm, D. & Egli, Marcel (2010). Application of free-flow isoelectric focusing to identify protein candidates changing under microgravity conditions. Proteomics, (10), 904-913.
  • Studer, M; Bradacs, G; Hilliger, A; Hürlimann, E; Engeli, S; Thiel, CS; Zeitner, P; Denier, B; Binggeli, M; Syburra, Th; Engelmann, F; Ullrich, O & Egli, Marcel (2010). Parabolic maneuvers of the Swiss Air Force fighter jet F-5E as a research platform for cell culture experiments in microgravity. Acta Astronautica, (68), 1729-1741.
  • Toy, MF; Pache, C; Parent, J; Kühn, J.; Egli, Marcel & Depeursinge, C (2010). Dual-mode digital holographic and fluorescence microscopy for the study of morphological changes in cells under simulated microgravity. Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing, (16), 7570-7573.
  • Pache, C; Westphal, K; Parent, J; Franco-Obregón, Alfredo; Depeursinge, C & Egli, Marcel (2010). Digital holographic microscopy real-time monitoring of cytoarchitectural alterations during simulated microgravity. J Biomed Opt, 26021-1-26021-9.
  • Ulbrich, C.; Westphal, K; Baatout, S; Wehland, M; Bauer, J.; Infanger, M.; Kreutz, R; Vadrucci, S; Cogoli, A; Grimm, D.; Derradji, H & Egli, Marcel (2008). Effects of basic fibroblast growth factor on endothelial cells under conditions of simulated microgravity. J Cell Biochem, (104), 1324-1341. doi: https://doi.org/10.1002/jcb.21710
  • Monici, M.; Romano, G; Cialdai, F; Fusi, F; Marziliano, N; Benvenuti, S; Cellai, I; Egli, Marcel & Cogoli, A (2008). Gravitational/mechanical factors affect gene expression profile. J Grav Physiol, (15), 191-192.
  • Pache, C; Westphal, K; Parent, J; Franco-Obregón, Alfredo; Depeursinge, C & Egli, Marcel (2008). Digital holographic microscopy for the study of morphological changes in cells under simulated microgravity condition. J Grav Physiol, (15), 237-238. doi: https://doi.org/10.1117/1.3377960
  • Cogoli, A & Egli, Marcel (2008). Cell biology in space: Basic Research and potential applications. Infocus, (12), 51-63.
  • Egli, Marcel & Cogoli, A (2008). Cell biology in space: Basic Research and potential applications. Infocus, 51-63.
  • Bertram, R.; Toporikova, N.; Freeman, ME & Egli, Marcel (2006). A mathematical model for the mating-induced prolactin rhythm of female rats. Am J Physiol, (290), 573-582. doi: https://doi.org/10.1152/ajpendo.00428.2005
  • Egli, Marcel; Sellix, M.T.; Poletini, MO & Bosworth, MD (2006). Anatomical and functional characterization of clock gene expression in neuroendocrine dopaminergic neurons. Am J Physiol, (209), 1309-1323.
  • Egli, Marcel; Toporikova, N.; Sellix, M.T.; Blanco, W.; Bosworth, MD; Bertram, R. & Freeman, M.E. (2006). Prolactin secretory rhythm of mated rats induced by a bolus injection of oxytocin. Am J Physiol, (290), 566-572.
  • Sellix, M. T.; Egli, Marcel; Poletini, MO; McKee, DT; Bosworth, MD; Fitch, CA & Freeman, M.E. (2006). Anatomical and functional characterization of clock gene expression in neuroendocrine dopaminergic neurons. Am J Physiol, (290), 1309-1323.
  • Toporikova, N.; Sellix, M.T.; Blanco, W.; Bosworth, MD; Bertram, R.; Fitch, CA; Freeman, M. E. & Egli, Marcel (2006). Prolactin secretory rhythm of mated rats induced by a single injection of oxytocin. Am J Physiology, 2005(290), 566-572. doi: https://dx.doi.org/10.1152%2Fajpendo.00427.2005
  • Egli, Marcel; Betram, R; Cogoli-Greuter, M & Vadrucci, S (2005). Are clock genes involved in altered circadian rhythms during space flight? J Grav Physiol, (12), 233-236.
  • Bertram, R.; Sellix, M.T.; Freeman, M.E. & Egli, Marcel (2004). Rhythmic secretion of prolactin in rats: Action of oxytocin coordinated by vasoactive intestinal polypeptide of suprachiasmatic nucleus origin. Endocrinology, (145), 3386-3394. doi: https://doi.org/10.1210/en.2003-1710
  • Sellix, M.T.; Henderson, R. P.; Freeman, M.E. & Egli, Marcel (2004). Ovarian steroid hormones modulate circadian rhythms of neuroendocrine dopaminergic neuronal activity. Brain Res, (1005), 168-185. doi: https://doi.org/10.1016/j.brainres.2004.01.049
  • Sunn, N.; Egli, Marcel; Burazin, T. C.; Burns, P.; Colvill, L.; Davern, P.; Denton, D. A.; Oldfield, B. J.; Weisinger, R. S.; Rauch, M.; Schmid, H.A. & McKinley, M. J. (2002). Circulating relaxin acts on subfornical organ neurons to stimulate water drinking in the rat. PNAS, (99), 1701-1706.
  • Berger, Th.; Imboden, H. & Egli, Marcel (2002). Angiotensin II influences the hyperpolarisation-activated current Ih in neurones of the rat paraventricular nucleus. Neurosci Lett, (330), 53-56. doi: https://doi.org/10.1016/s0304-3940(02)00736-x
  • Egli, Marcel; Laurent, J. P.; Mosimann, R.; Felix, D. & Imboden, H. (2000). Morphological and immunocytochemical characterisation of electrophysiologically investigated neurons in the PVN of the rat. J Neurosci Methods, (95), 145-150.

Publikationen und Präsentationen - Buchkapitel/Gesetzeskommentar/Lexikonartikel

  • Granata, Timothy & Egli, Marcel (2016). Bionutrients. In ESA (Hrsg.), Bionutrients (S. 6-30). Netherlands: ESA.
  • Granata, Timothy; Krehel, Marek; Wittkopf, Stephen & Egli, Marcel (2015). A hybrid facade that combines an algal bioreactor with photovoltaics. In Jean-Louis Scartezzini (Hrsg.), Proceedings of International Conference CISBAT 2015: Future Buildings and Districts Sustainability from Nano to Urban Scale: Vol. 2 (S. 567-572). Lausanne: EPFL.
  • Tronci, E; Mancini, T; Salvo, I; Sinisi, S; Mari, F.; Melatti, I; Massini, A; David, A. Basin; Dierkesy, A; Ehrigy, R; Röblitzy, S.; Leeners, B.; Krüger, THC; Egli, Marcel & Ille, F. (2014). Patient-Specific Models from Inter-Patient Biological. Proceedings of FMCAD (S. 2-8). xxx: xxx.
  • Egli, Marcel (2011). Sounding rocket and balloon activities and related Research in Switzerland 2009 - 2011. Proceedings of the 20th ESA Symposium on European rocket and balloon programmes and related research (S. 221-232). NL: ESA.
  • Egli, Marcel (2009). Humans in Earth orbit - what effect does it have? In L. Codignola, K.-U. Schrogel (Hrsg.), Humans in outer space – Interdisciplinary odysseys (S. 252-255). Wien /New York: Springer.
  • Freeman, M.E.; McKee, DT; Egli, Marcel & Bertram, R. (2008). Biological and mathematical modelling approaches to defining the role of oxytocin and dopamine in the control of mating-induced PRL secretion. In R.S. Bridges (Hrsg.), Neurobiology of the parental brain (S. 133-136). Elsevier: Academic Press.

Publikationen und Präsentationen - Bericht/Working Paper

  • Egli, Marcel; Richard, Stéphane & Wüest, Simon (2014). A Novel Microgravity Simulator Applicable for Three-Dimensional Cell Culturing (Microgravity Science and Technology).

Publikationen und Präsentationen - Präsentation (Tagungsbeitrag/Referat/Vortrag)

  • Egli, Marcel (02.03.2012). Bio-medical Research in Space. Bio-medical Research, Göttingen.
  • Egli, Marcel (11.11.2011). Space Biology Group - Research and Space Support Center. United Nations Assembly, Vienna, Austria.
  • Chooi, Y.; Benavides Damm, Tatiana; Traxler, J.; Unternährer, S; Kisielow, M; Beyer, C.; Egli, Marcel & Franco-Obregón, Alfredo (30.09.2010). Pulsed Electromagnetic Fields Induce Immediate Changes in Cytoskeletal Arrangement by Activating Cellular Mechanotransduction Pathways. 4th Mechanobiology Workshop and Biophysical Society Joint Meeting, Singapore.
  • Toy, MF; Kühn, J.; Parent, J; Pache, C; Depeursinge, C & Egli, Marcel (05.05.2010). Real time 3-D cytomorphological imaging using digital holographic microscopy and flueorescence microscopy for space biology. DH, s.
  • Schaffhauser, DF; Forster, I.; Egli, Marcel & Dittrich, PS (02.02.2010). A microfluidic device for electrophysiological measurements on Xenopus oocytes under zero gravity. Lab-on-a-chip European congress, Dublin, Ireland.
  • Schaffhauser, DF; Franco-Obregón, Alfredo; Forster, I.; Dittrich, PS & Egli, Marcel (16.09.2009). Microfluidic chip for patch clamping in microgravity. Analytical Chemistry Symposium “Analyze That”, Zurich.
  • Egli, Marcel (23.01.2009). Electrophysiological study of cellular effects of weightlessness induced muscle atrophy. ESA Parabolic Flight Symposium, Noordwjik, Netherlands.
  • Westphal, K; Vadrucci, S; Franco-Obregón, Alfredo & Egli, Marcel (10.09.2008). Influence of altered gravity on clock gene expression in rat-1 fibroblasts. ESA Life Science Symposium, Angers, France.
  • Pache, C; Westphal, K; Parent, J; Franco-Obregón, Alfredo; Depeursinge, C & Egli, Marcel (14.05.2008). Digital holographic microscopy for the study of morphological changes in cells under simulated microgravity condition. ESA Life Science Symposium, Angers, France.
  • Sirzen-Zelenskaya, A.; Bertram, R.; Freeman, M.E.; Gerber, U. & Egli, Marcel (17.10.2007). Influence of prolactin on oxytocin-containing neurons in the paraventricular nucleus. Meeting of the Endocrine Society, Toronto, Canada.
  • Freeman, M.E.; McKee, DT; Egli, Marcel & Bertram, R. (05.07.2007). Biological and mathematical modeling approaches to defining the role of oxytocin and dopamine in the control of mating-induced prolactin secretion. Parental Brain Conference, Boston, MA.
  • Vadrucci, S; Cogoli-Greuter, M & Egli, Marcel (05.06.2006). Influence of Altered Gravity on Clock Gene Expression in Rat-1 Fibroblasts. Meeting of the Society for Research on Biological Rhythms, Sandestin, FL.
  • Egli, Marcel; Bertram, R.; Sellix, M.T.; Toporikova, N. & Freeman, ME (15.04.2004). Oxytocin as a Prolactin-releasing factor: Joint biological and mathematical studies. Meeting of the Society for Neuroscience, San Diego, CA.
  • Egli, Marcel; Freeman, ME & Sellix, M.T. (23.04.2003). Vasoactive intestinal peptide of suprachiasmatic nucleus origin controls prolactin and oxytocin secretion in pseudopregnant rats. Meeting of the Endocrine Society, Philadelphia, PA.
  • Egli, Marcel; Bertram, R. & Freeman, ME (13.03.2003). Computational model of the hypothalamo-hypophyseal neuronal network regulating the release of Prolactin in rats. Meeting of the Society for Neuroscience, New Orleans, LA.
  • Egli, Marcel; Berger, Th. & Imboden, H. (14.02.2001). Angiotensin II influences the hyperpolarisation-activated current Ih in neurones of the rat paraventricular nucleus. International Congress of Physiological Sciences, Christchurch, NZ.

bedeutende Leistung

    • Egli, Marcel. Member. (2008). Swiss Academy of Science.

    • Egli, Marcel. Member of the expert advisory board. (2007). Swiss Aerospace Cluster.

    • Egli, Marcel. European Science Foundation Evaluator of FP7 Space calls. (2005). European Commision.

    • Egli, Marcel. Swiss Delegate. (2005). ESA.

    • Egli, Marcel. Space Research Expert. (2005). Canadian Space Agency.

bedeutende Leistung - Kommissionen, Mitgliedschaften und externe Tätigkeiten

  • Egli, Marcel. Member. (2008). Swiss Academy of Science.
  • Egli, Marcel. Member of the expert advisory board. (2007). Swiss Aerospace Cluster.
  • Egli, Marcel. European Science Foundation Evaluator of FP7 Space calls. (2005). European Commision.
  • Egli, Marcel. Swiss Delegate. (2005). ESA.
  • Egli, Marcel. Space Research Expert. (2005). Canadian Space Agency.